R&D

Pioneering a sustainable future through continuous innovation from functional probiotics to natural solutions and pet care.

Pioneering a sustainable future through continuous innovation from
functional probiotics to natural solutions and pet care.

Pioneering a sustainable future through continuous innovation from functional probiotics to natural solutions and pet care.

Natural Ingredients

By combining the limitless potential of nature with hy’s technological expertise, we create greater value.

By combining the limitless potential of nature with hy’s technological expertise,
we create greater value.

By combining the limitless potential of nature with hy’s technological expertise, we create greater value.

Joint Health: Tiger Lily Bulb ExtractIndividually Approved Functional Ingredient

  • Individually
    Approved
    Ingredient
    (No. 2023-43)
    개별인정형
    원료
    (No. 2023-43)
  • Functional ingredient for joint health
  • Ingestion safety
  • Clinically Proven Ingredient
Ingredient Information
Key Ingredients
  • Tiger lily bulb extract powder
Functional benefits
  • Relieves joint discomfort
Daily intake
  • 1,000 mg
Ingredient Strength
  • Tiger lily
  • A medicinal plant with a long history of use
  • Pleasant Taste and Easy Application
    ‘Applicable to various formulations’
  • Efficacy evaluation using beagle dog model
  • Clinical study: Improvement in six joint health indicators
Research papers
  • Survivability in the human body and inhibition of vaginitis-causing bacteria demonstrated in in vitro and in vivo studies
  • Inhibition of inflammation in joint cells demonstrated in an in vivo study
  • Improvement in pain and inflammation markers demonstrated in an in vivo study
  • Improvement in joint cartilage tissue damage demonstrated in an in vivo study
  • Improvement in joint health indicators (K-WOMAC) and joint pain relief demonstrated in the clinical study
Patent
  • Food formulation for arthritis prevention, developed under the Ministry of Agriculture, Food and Rural Affairs – a government-funded project
    Food formulation for arthritis prevention, developed under the Ministry of Agriculture, Food and Rural Affairs – a government-funded project
    Food formulation for arthritis prevention, developed under the Ministry of Agriculture, Food and Rural Affairs – a government-funded project
Results of Human Clinical Trial
Clinical Trial Design
  • A total of 100 men and women aged 50 and above with joint discomfort were randomly assigned in a double-blind, 12-week study. Participants received a daily intake of 1 gram.
    A total of 100 men and women aged 50 and above with joint discomfort were randomly assigned in a double-blind, 12-week study. Participants received a daily intake of 1 gram.
    A total of 100 men and women aged 50 and above with joint discomfort were randomly assigned in a double-blind, 12-week study. Participants received a daily intake of 1 gram.
Improvement in pain
  • Significant improvement in pain was observed. A statistically significant difference was found when comparing pre- and post-intake values. Significant between-group differences were also confirmed at each visit.
    Significant improvement in pain was observed. A statistically significant difference was found when comparing pre- and post-intake values. Significant between-group differences were also confirmed at each visit.
    Significant improvement in pain was observed. A statistically significant difference was found when comparing pre- and post-intake values. Significant between-group differences were also confirmed at each visit.
Improvement in pain and joint function
  • A statistically significant difference between the two intake groups was observed when comparing before and after intake / A statistically significant difference between the two intake groups was confirmed at each visit.
    A statistically significant difference between the two intake groups was observed when comparing before and after intake / A statistically significant difference between the two intake groups was confirmed at each visit.
    A statistically significant difference between the two intake groups was observed when comparing before and after intake / A statistically significant difference between the two intake groups was confirmed at each visit.
  • Decrease in K-WOMAC score
    45%
  • Decrease in Pain VAS
    30.9%
Cartilage Health Indicators
  • Reduction in cartilage tissue damage
  • Reduction in inflammation markers: TNF-α, IL-6, CRP, LTB-4, PGE-2
  • Inhibition of joint and cartilage-degrading enzymes: MMP-9