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R&D

Pioneering a sustainable future through continuous innovation from functional probiotics to natural solutions and pet care.

Pioneering a sustainable future through continuous innovation from
functional probiotics to natural solutions and pet care.

Pioneering a sustainable future through continuous innovation from functional probiotics to natural solutions and pet care.

Probiotics

With the distinct value of microbiome-based functional probiotics, we are setting new standards both in Korea and across the world.

With the distinct value of microbiome-based functional probiotics, we are setting new standards both in Korea and across the world.

FatSlim™ ProbioticsIndividually Approved Functional Ingredient

HY7601+KY1032

  • Individually
    Approved
    Probiotic
    (No. 2019-4, MFDS)
  • Supports Body Fat Loss
  • Dual-Fucntion Probiotic
  • Isolated from Kimchi
  • Clinically Proven Ingredient
  • Stable at Room Temperature
Ingredient Information
Key Ingredients
  • A probiotic blend of
    L. curvatus HY7601 and L. plantarum KY1032
Origin
  • Kimchi
Functional Benefits
  • Supports fat loss and weight management
Recommended daily intake
  • 1 x 1010 CFU
Ingredient Strength
  • Daily Intake: 10 billion CFU
  • The only plant-Based probiotic strain isolated from kimchi
  • Two human clinical trials conducted
  • Dual Functionality
    Fat Loss and Weight Management / Gut Health
Research Papers
  • Inhibition of adipocyte formation demonstrated in two in vitro studies
  • Improvement of high-fat diet-induced obesity demonstrated in two in vitro studies
  • Activation of fat metabolism and increased cholesterol excretion demonstrated in an in vitro study
  • Suppression of metabolic disorders caused by excessive fructose intake demonstrated in an in vitro study
  • Reduction of body fat and weight demonstrated in three clinical trials
  • Improvement of triglycerides demonstrated in an in vitro study
  • Improvement of blood triglyceride levels demonstrated in two clinical trial
Patents
  • Reduction of blood cholesterol and suppression of obesity
  • Improvement of hyperinsulinemia, hyperglycemia, and hypertriglyceridemia
  • Inhibition of adipocyte differentiation gene expression
Certifications
  • KMF Halal
    Certification
  • IR52
    Jang Young-Shil
    Award Winner
  • NDI status
Results of human clinical trials
Clinical Trial Design
  • Total of 72 overweight participants were randomly assigned in a double-blind study over 12 weeks, with a daily dose of 1 × 1010 CFU.
    Total of 72 overweight participants were randomly assigned in a double-blind study over 12 weeks, with a daily dose of 1 × 1010 CFU.
    Source: Mo et al., (2022), Nutrients, 15(12), 2484
Body Composition Analysis Results
  • Confirmed that FatSlim™ probiotics intake group showed significant decreases in six body measurement indices compared to the control group.
  • Weight
    -1.4kg
  • BMI
    -0.47kg/m²
  • Waist circumference
    -1.72cm
  • Body fat mass
    -0.67kg
  • Lean body mass
    -0.69kg
  • Visceral fat area
    -4.49cm²
Blood Analysis Results
  • Comparative analysis of FatSlim™ probiotics intake group and the control group
  • Leptin levels
    significantly decreased
    -3.99ng/mL
Leptin: A protein secreted by fat cells, it is a hormone related to appetite regulation and positively correlated with fat mass.
Leptin: A protein secreted by fat cells, it is a hormone related to appetite regulation and positively correlated with fat mass.
Leptin: A protein secreted by fat cells, it is a hormone related to appetite regulation and positively correlated with fat mass.
  • Adiponectin levels
    significantly increased
    +423.37ng/mL
Adiponectin: A protein secreted by fat cells, involved in regulating glucose levels and fatty acid breakdown, and negatively correlated with fat mass.
Microbiome Analysis Results
  • Compared to the control group, FatSlim™ probiotics intake group showed an increase in bacterial strains associated with weight loss and a decrease in strains associated with weight gain
  • Bacterial strains associated with weight loss
    • Bifidobacteriaceae
    • Akkermansiaceas
  • Bacterial strains associated with weight gain
    • Selenomonadaceas
    • Prevotelaceas
Principal coordinate analysis (PCoA)
  • Changes in gut microbiota in the control group and FatSlim™ probiotics intake group were observed.
  • Intake of FatSlim™ probiotics led to measurable changes
  • Control group : Before taking the placebo
  • Test group : Before taking FatSlim™ probiotics
  • Control group : after taking the placebo
  • Test group : after taking FatSlim™ probiotics
Sources : Mo et al., (2022), Nutrients, 15(12), 2484
Sources : Mo et al., (2022), Nutrients, 15(12), 2484
Pearson correlation analysis Pearson correlation analysis
Increased abundance of gut microbiota
  • An increased abundance of gut microbiota associated with body fat loss was observed after intake of FatSlim™ probiotics
    An increased abundance of gut microbiota associated with body fat loss was observed after intake of FatSlim™ probiotics
Bifidobacterium family & Akkermansia genus
Decreased abundance of gut microbiota
  • An decreased abundance of gut microbiota associated with body fat gain was observed after intake of FatSlim™ probiotics
    An decreased abundance of gut microbiota associated with body fat gain was observed after intake of FatSlim™ probiotics
    An decreased abundance of gut microbiota associated with body fat gain was observed after intake of FatSlim™ probiotics
Faecalibacterium Prausnitizii, Prevotella copri & Coliinsella aerofaciens
Faecalibacterium Prausnitizii, Prevotella copri & Coliinsella aerofaciens